1424433-17-9
Chemical Structure
Disulfo-Cy3 NHS ester
- CAS No.: 1424433-17-9
- Formula:C34H39N3O10S2
- Molecular Weight:713.82
InChIKey: VPXBTKGDPSNVSM-UHFFFAOYSA-N
SMILES: O=C(CCCCC[N+]1=C(/C=C/C=C2N(C)C3=CC=C(S(=O)(O)=O)C=C3C\2(C)C)C(C)(C)C4=C1C=CC(S(=O)([O-])=O)=C4)ON5C(CCC5=O)=O
Biological Activity: Disulfo-Cy3 NHS ester is a fluorescent dye used for plasma membrane protein labeling and detection antibody labeling. Disulfo-Cy3 NHS ester can covalently bind to amino groups on cell surface proteins or detection antibodies. Disulfo-Cy3 NHS ester lacks a low-affinity membrane anchoring site, avoiding transient binding to lipid membranes. Disulfo-Cy3 NHS ester, via a conjugated detection antibody, enables visualization and detection of on-cell immune sandwich structures targeting secreted proteins (Ex/Em = 550/570 nm)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Disulfo-Cy3 NHS ester | Disulfo-Cy3 NHS ester is a fluorescent dye used for plasma membrane protein labeling and detection antibody labeling. Disulfo-Cy3 NHS ester can covalently bind to amino groups on cell surface proteins or detection antibodies. Disulfo-Cy3 NHS ester lacks a low-affinity membrane anchoring site, avoiding transient binding to lipid membranes. Disulfo-Cy3 NHS ester, via a conjugated detection antibody, enables visualization and detection of on-cell immune sandwich structures targeting secreted proteins (Ex/Em = 550/570 nm). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Aknine N, et al. Lipid-Directed Covalent Labeling of Plasma Membranes for Long-Term Imaging, Barcoding and Manipulation of Cells. JACS Au. 2025 Feb 24;5(2):922-936.
- [2]. Li Y, et al. Deciphering single-cell protein secretion and gene expressions by constructing cell-antibody conjugates. Bioorganic chemistry. 2024 Feb;143:106987.
