142702-31-6
142702-31-6
Chemical Structure
DTSSP Crosslinker disodium
- CAS No.: 142702-31-6
- Formula:C14H14N2Na2O14S4
- Molecular Weight:608.51
IUPAC Name: sodium 1,1'-((3,3'-disulfanediylbis(propanoyl))bis(oxy))bis(2,5-dioxopyrrolidine-3-sulfonate)
InChIKey: XRWWBWZHHSXBNC-UHFFFAOYSA-L
SMILES: O=C(ON1C(C(S(=O)([O-])=O)CC1=O)=O)CCSSCCC(ON2C(C(S(=O)([O-])=O)CC2=O)=O)=O.[Na+].[Na+]
Biological Activity: DTSSP Crosslinker disodium is a protein cross-linker containing a disulfide bond. DTSSP Crosslinker disodium can react with sidechains of amino acids that are within close proximity[1][2].
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DTSSP Crosslinker disodium | DTSSP Crosslinker disodium is a protein cross-linker containing a disulfide bond. DTSSP Crosslinker disodium can react with sidechains of amino acids that are within close proximity. | |||||||||||||||||||||
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References
- [1]. Swaim CL, Smith JB, Smith DL. Unexpected products from the reaction of the synthetic cross-linker 3,3'-dithiobis(sulfosuccinimidyl propionate), DTSSP with peptides. J Am Soc Mass Spectrom. 2004;15(5):736-749. [Content Brief]
- [2]. Anabuki T, et al. Identification of recombinant AtPYL2, an abscisic acid receptor, in E. coli using a substrate-derived bioactive small molecule, a biotin linker with alkyne and amino groups, and a protein cross-linker. Bioorg Med Chem Lett. 2019;29(21):126634. [Content Brief]
