142828-12-4
142828-12-4
Chemical Structure
5-Oxo-15-HETE
- CAS No.: 142828-12-4
- Formula:C20H30O4
- Molecular Weight:334.45
InChIKey: RIUDRKHGFDAKPO-WWWYWCMOSA-N
SMILES: CCCCC[C@H](O)/C=C/C=C\C/C=C\C=C\C(CCCC(O)=O)=O
Biological Activity: 5-Oxo-15-HETE is a derivative of 5-Oxo-ETE (HY-112549). 5-Oxo-15-HETE is generated from 5-Oxo-ETE by 15-LO. 5-Oxo-15-HETE is approximately eight times less potent than 5-Oxo-ETE in inducing Ca2+ mobilization. 5-Oxo-15-HETE exhibits chemotactic activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5-Oxo-15-HETE | 5-Oxo-15-HETE is a derivative of 5-Oxo-ETE (HY-112549). 5-Oxo-15-HETE is generated from 5-Oxo-ETE by 15-LO. 5-Oxo-15-HETE is approximately eight times less potent than 5-Oxo-ETE in inducing Ca2+ mobilization. 5-Oxo-15-HETE exhibits chemotactic activity. | |||||||||||||||||||||
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References
- [1]. Kühn H. Biosynthesis, metabolization and biological importance of the primary 15-lipoxygenase metabolites 15-hydro(pero)XY-5Z,8Z,11Z,13E-eicosatetraenoic acid and 13-hydro(pero)XY-9Z,11E-octadecadienoic acid. Prog Lipid Res. 1996 Sep;35(3):203-26.
- [2]. Patel P, et al. 5-oxo-15-HETE: total synthesis and bioactivity. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1857-60.
