142864-19-5
142864-19-5
Chemical Structure
Enlimomab
Synonym(s): BI-RR 0001; Anti-Human IL6 Recombinant Antibody
- CAS No.: 142864-19-5
- Formula:N/A
- Molecular Weight:(147.1 kDa)
IUPAC Name: ethyl homoserinate
SMILES: [Enlimomab]
Biological Activity: Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research[1] [2] .
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Enlimomab | 95.00% | Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research . | ||||||||||||||||||||
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References
- [1]. J Vuorte, et al. Anti-ICAM-1 monoclonal antibody R6.5 (Enlimomab) promotes activation of neutrophils in whole blood. J Immunol. 1999 Feb 15;162(4):2353-7. [Content Brief]
- [2]. [2]Gregory J del Zoppo. Acute anti-inflammatory approaches to ischemic stroke. Ann N Y Acad Sci. 2010 Oct;1207:143-8. [Content Brief]
