143323-55-1
143323-55-1
Chemical Structure
L-012
- CAS No.: 143323-55-1
- Formula:C13H9ClN4O2
- Molecular Weight:288.69
IUPAC Name: 8-amino-5-chloro-7-phenyl-2,3-dihydropyrido[3,4-d]pyridazine-1,4-dione
InChIKey: ABEDICJFYSFCHB-UHFFFAOYSA-N
SMILES: O=C(C1=C2C(Cl)=NC(C3=CC=CC=C3)=C1N)NNC2=O
Biological Activity: L-012 is a luminal-based chemiluminescent probe. L-012 sodium salt can detect NADPH oxidase (Nox)-derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS))[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L-012 | 99.63% | L-012 is a luminal-based chemiluminescent probe. L-012 sodium salt can detect NADPH oxidase (Nox)-derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS)). | ||||||||||||||||||||
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References
- [1]. Imada I, et al. Analysis of reactive oxygen species generated by neutrophils using a chemiluminescence probe L-012[J]. Analytical biochemistry, 1999, 271(1): 53-58. [Content Brief]
- [2]. Kielland A, et al. In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic Biol Med. 2009;47(6):760-766. [Content Brief]
