1433857-09-0
Chemical Structure
Lascufloxacin hydrochloride
Synonym(s): KRP-AM1977 hydrochloride
- CAS No.: 1433857-09-0
- Formula:C21H25ClF3N3O4
- Molecular Weight:475.89
IUPAC Name: 7-((3S,4S)-3-((cyclopropylamino)methyl)-4-fluoropyrrolidin-1-yl)-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
InChIKey: YQHZQIJEMFMUGH-DFIJPDEKSA-N
SMILES: O=C(O)C1=CN(C2=C(C1=O)C=C(C(N3C[C@@H]([C@@H](C3)F)CNC4CC4)=C2OC)F)CCF.Cl
Biological Activity: Lascufloxacin (KRP-AM1977) hydrochloride is a potent antibacterial compound candidate with broad-spectrum activity against various clinical isolates. Lascufloxacin hydrochloride shows the most potent activity against Gram-positive bacteria compared to other tested quinolones. Lascufloxacin hydrochloride demonstrates incomplete cross-resistance against existing quinolone-resistant strains. Lascufloxacin hydrochloride has potent inhibitory activity against both wild-type and mutated target enzymes.
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Lascufloxacin hydrochloride | Lascufloxacin (KRP-AM1977) hydrochloride is a potent antibacterial compound candidate with broad-spectrum activity against various clinical isolates. Lascufloxacin hydrochloride shows the most potent activity against Gram-positive bacteria compared to other tested quinolones. Lascufloxacin hydrochloride demonstrates incomplete cross-resistance against existing quinolone-resistant strains. Lascufloxacin hydrochloride has potent inhibitory activity against both wild-type and mutated target enzymes. | |||||||||||||||||||||
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