1434515-70-4
1434515-70-4
Chemical Structure
UCSF924
- CAS No.: 1434515-70-4
- Formula:C20H22N2O2
- Molecular Weight:322.40
IUPAC Name: 6-methyl-2-(((3-phenoxypropyl)amino)methyl)quinolin-4-ol
InChIKey: RPHDOVLXDYWDGF-UHFFFAOYSA-N
SMILES: OC1=CC(CNCCCOC2=CC=CC=C2)=NC3=CC=C(C)C=C13
Biological Activity: UCSF924, a chemical probe, is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM. UCSF924 has no off-target effects on more than 320 non-olfactory GPCRs. UCSF924 can be used for research in the field of neuropsychiatric diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
UCSF924 | 99.53% | UCSF924, a chemical probe, is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM. UCSF924 has no off-target effects on more than 320 non-olfactory GPCRs. UCSF924 can be used for research in the field of neuropsychiatric diseases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Wang S, et al. D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. Science. 2017 Oct 20;358(6361):381-386. [Content Brief]
- [2]. Thomas G E. Characterizing antipsychotic behavioral and corticostriatal neurophysiological effects to psychotomimetic challenge. Duke University, 2022.
