144025-82-1
Chemical Structure
PACAP-38 (16-38), human, mouse, rat
- CAS No.: 144025-82-1
- Formula:C123H215N39O28S
- Molecular Weight:2720.33
SMILES: OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@H](C(N)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC(CNC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CCSC)NC([C@@H](N)CCC(N)=O)=O)=O)=O)=O)=O)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: PACAP-38 (16-38), human, mouse, rat is a peptide fragment encompassing the C-terminal 16-38 segment of PACAP (1-38), human, ovine, rat (HY-P0221). PACAP-38 (16-38), human, mouse, rat lacks the N-terminal 1-15 receptor activation core, but retains the ability to bind to the PAC/VPAC receptor family (PAC1/VPAC1/VPAC2 receptor). PACAP-38 (16-38), human, mouse, rat promotes histamine release and exerts a certain degree of hypotensive effect[1][2].
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PACAP-38 (16-38), human, mouse, rat | PACAP-38 (16-38), human, mouse, rat is a peptide fragment encompassing the C-terminal 16-38 segment of PACAP (1-38), human, ovine, rat (HY-P0221). PACAP-38 (16-38), human, mouse, rat lacks the N-terminal 1-15 receptor activation core, but retains the ability to bind to the PAC/VPAC receptor family (PAC1/VPAC1/VPAC2 receptor). PACAP-38 (16-38), human, mouse, rat promotes histamine release and exerts a certain degree of hypotensive effect. | |||||||||||||||||||||
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References
- [1]. Mori T, et al. Histamine release induced by pituitary adenylate cyclase activating polypeptide from rat peritoneal mast cells. Arzneimittel-Forschung. 1994 Sep;44(9):1044-6. [Content Brief]
- [2]. Absood A, et al. Vascular effects of pituitary adenylate cyclase activating peptide: a comparison with vasoactive intestinal peptide. Regulatory peptides. 1992 Aug 13;40(3):323-9. [Content Brief]
