1440903-11-6
1440903-11-6
Chemical Structure
MMA-NODAGA
- CAS No.: 1440903-11-6
- Formula:C21H31N5O9
- Molecular Weight:497.50
InChIKey: SJUXYJQNMNJVFX-UHFFFAOYSA-N
SMILES: O=C(CN1CCN(CCN(C(CCC(NCCN2C(C=CC2=O)=O)=O)C(O)=O)CC1)CC(O)=O)O
Biological Activity: MMA-NODAGA is a chelator for site-specific labeling of targeting proteins containing unpaired cysteine. MMA-NODAGA can be used to conjugate with exosome and 64Cu in image with positron emission tomography (PET)[1][2].
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MMA-NODAGA | MMA-NODAGA is a chelator for site-specific labeling of targeting proteins containing unpaired cysteine. MMA-NODAGA can be used to conjugate with exosome and 64Cu in image with positron emission tomography (PET). | |||||||||||||||||||||
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References
- [1]. Sara F F Almeida , et al. Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis. Small. 2022 Dec;18(49):e2203999. [Content Brief]
- [2]. Mohamed Altai, et al. Influence of nuclides and chelators on imaging using affibody molecules: comparative evaluation of recombinant affibody molecules site-specifically labeled with ⁶⁸Ga and ¹¹¹In via maleimido derivatives of DOTA and NODAGA. Bioconjug Chem. 2013 Jun 19;24(6):1102-9. [Content Brief]
