1443983-36-5
1443983-36-5
Chemical Structure
GDC-0927 Racemate
Synonym(s): SRN-927 Racemate
- CAS No.: 1443983-36-5
- Formula:C28H28FNO4
- Molecular Weight:461.52
IUPAC Name: 2-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-chromen-6-ol
InChIKey: KJAAPZIFCQQQKX-UHFFFAOYSA-N
SMILES: OC1=CC=C2C(C(C)=C(C3=CC=CC(O)=C3)C(C4=CC=C(OCCN5CC(CF)C5)C=C4)O2)=C1
Biological Activity: GDC-0927 Racemate (SRN-927 Racemate) is an estrogen receptor (ER) degrader that can effectively inhibit the activity of ER-α with an IC50 value of 0.2 nM and can be used in diseases related to estrogen receptors.
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GDC-0927 Racemate | GDC-0927 Racemate (SRN-927 Racemate) is an estrogen receptor (ER) degrader that can effectively inhibit the activity of ER-α with an IC50 value of 0.2 nM and can be used in diseases related to estrogen receptors. | |||||||||||||||||||||
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