144425-86-5
144425-86-5
Chemical Structure
BW-1003C87 Ethylsulfate
- CAS No.: 144425-86-5
- Formula:C12H13Cl3N4O3S
- Molecular Weight:399.68
IUPAC Name: 5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethanesulfonate
InChIKey: NVKJAOGJEDODFZ-UHFFFAOYSA-N
SMILES: CCS(=O)(O)=O.NC1=NC(N)=NC=C1C2=C(C(Cl)=CC(Cl)=C2)Cl
Biological Activity: BW-1003C87 Ethylsulfate is a glutamate release inhibitor. BW-1003C87 Ethylsulfate exhibit neuroprotective effect. BW-1003C87 Ethylsulfate can elevate seizure threshold. BW-1003C87 Ethylsulfate can be used for the research of neurological disease, such as ischemic and seizure[1][2][3].
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BW-1003C87 Ethylsulfate | BW-1003C87 Ethylsulfate is a glutamate release inhibitor. BW-1003C87 Ethylsulfate exhibit neuroprotective effect. BW-1003C87 Ethylsulfate can elevate seizure threshold. BW-1003C87 Ethylsulfate can be used for the research of neurological disease, such as ischemic and seizure. | |||||||||||||||||||||
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References
- [1]. Gilland E, et al. Hypoxic-ischemic injury in the neonatal rat brain: effects of pre- and post-treatment with the glutamate release inhibitor BW1003C87. Brain Res Dev Brain Res. 1994 Nov 18;83(1):79-84. [Content Brief]
- [2]. Morimoto K, et al. BW1003C87, phenytoin and carbamazepine elevate seizure threshold in the rat amygdala-kindling model of epilepsy. Eur J Pharmacol. 1997 Nov 19;339(1):11-5. [Content Brief]
- [3]. Gaspary HL, et al. BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis. Eur J Pharmacol. 1994 Sep 12;262(3):197-203. [Content Brief]
