144631-82-3
144631-82-3
Chemical Structure
Bromoriluzole
- CAS No.: 144631-82-3
- Formula:C8H4BrF3N2OS
- Molecular Weight:313.09
IUPAC Name: 4-bromo-6-(trifluoromethoxy)benzo[d]thiazol-2-amine
InChIKey: UGMJJOPHHBHLNL-UHFFFAOYSA-N
SMILES: FC(F)(F)OC=1C=C(Br)C=2N=C(SC2C1)N
Biological Activity: Bromoriluzole is a derivative of Riluzole (HY-B0211). Bromoriluzole inhibits Ca2+ -dependent Calmodulin-SK4 channel interaction. Bromoriluzole is used for the research of neurodegenerative diseases[1].
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Bromoriluzole | Bromoriluzole is a derivative of Riluzole (HY-B0211). Bromoriluzole inhibits Ca2+ -dependent Calmodulin-SK4 channel interaction. Bromoriluzole is used for the research of neurodegenerative diseases. | |||||||||||||||||||||
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References
- [1]. Baltasar-Marchueta M, et al. Identification of Riluzole derivatives as novel calmodulin inhibitors with neuroprotective activity by a joint synthesis, biosensor, and computational guided strategy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 May;174:116602. [Content Brief]
