1446311-56-3

SMN-C2 Chemical Structure
1446311-56-3

Chemical Structure

SMN-C2

  • CAS No.: 1446311-56-3
  • Formula:C24H27N5O2
  • Molecular Weight:417.50

IUPAC Name: (S)-3-(6,8-dimethylimidazo[1,2-a]pyrazin-2-yl)-7-(4-ethyl-3-methylpiperazin-1-yl)-2H-chromen-2-one

InChIKey: PETSCYDXCUXNIW-INIZCTEOSA-N

SMILES: O=C1C(C2=CN3C(C(C)=NC(C)=C3)=N2)=CC4=CC=C(N5C[C@H](C)N(CC)CC5)C=C4O1

Biological Activity: SMN-C2, an analog of RG-7916, is a selective modulator of SMN2 gene splicing that acts by binding SMN2 pre-mRNA, thereby increasing far upstream element binding protein 1 (FUBP1) and KH-spliced RNA binding Protein affinity regulator protein (KHSRP) to the SMN2 pre-mRNA complex. SMN-C2 can be used in spinal muscular atrophy (SMA) research[1].

Cat. No. Product Name Purity Description Pricing
HY-124648
SMN-C2 98.85% SMN-C2, an analog of RG-7916, is a selective modulator of SMN2 gene splicing that acts by binding SMN2 pre-mRNA, thereby increasing far upstream element binding protein 1 (FUBP1) and KH-spliced RNA binding Protein affinity regulator protein (KHSRP) to the SMN2 pre-mRNA complex. SMN-C2 can be used in spinal muscular atrophy (SMA) research.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References