1446991-36-1
Chemical Structure
Sarafotoxin S6d
Synonym(s): STX-b
- CAS No.: 1446991-36-1
- Formula:C112H163N27O34S5
- Molecular Weight:2591.98
SMILES: O=C([C@@H](N)CSSC[C@H](NC1=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC2=CNC3=CC=CC=C23)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CC(O)=O)=O)CCC(N)=O)=O)CC4=CNC=N4)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]5CCC(O)=O)=O)CCCCN)=O)CC(O)=O)=O)[C@@H](C)O)=O)CCSC)=O)CC(O)=O)=O)CCCCN)=O)CSSC[C@H](NC5=O)C(N[C@H](C(N[C@H](C(N[C@H]1CC6=CC=CC=C6)=O)CC7=CC=C(O)C=C7)=O)CC(C)C)=O)=O)[C@@H](C)O
Biological Activity: Sarafotoxin S6d (STX-b) is a polypeptide toxin isolated from the venom of the Israeli sand boa constrictor. Sarafotoxin S6d induces multiple electrocardiogram (ECG) changes including myocardial ischemia and hyperkalemia. Sarafotoxin S6d induces strong extracellular calcium-dependent vasoconstriction in rat aorta and exhibits positive inotropic effects in rat atria. Sarafotoxin S6d can be used in the study of cardiovascular diseases[1].
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Sarafotoxin S6d | Sarafotoxin S6d (STX-b) is a polypeptide toxin isolated from the venom of the Israeli sand boa constrictor. Sarafotoxin S6d induces multiple electrocardiogram (ECG) changes including myocardial ischemia and hyperkalemia. Sarafotoxin S6d induces strong extracellular calcium-dependent vasoconstriction in rat aorta and exhibits positive inotropic effects in rat atria. Sarafotoxin S6d can be used in the study of cardiovascular diseases. | |||||||||||||||||||||
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