144702-17-0
Chemical Structure
Pomisartan
- CAS No.: 144702-17-0
- Formula:C31H30N4O2
- Molecular Weight:490.60
IUPAC Name: 4'-((2-ethyl-4-methyl-6-(5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-yl)-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid
InChIKey: SOYCBUUKISWFER-UHFFFAOYSA-N
SMILES: O=C(C1=C(C2=CC=C(CN3C4=CC(C5=CN(CCCC6)C6=N5)=CC(C)=C4N=C3CC)C=C2)C=CC=C1)O
Biological Activity: Pomisartan is an orally active angiotensin II receptor type AT1 antagonist (IC50=0.26 μM). Pomisartan works by inhibiting the binding of angiotensin II to the AT1 receptor, thereby blocking the vasoconstriction and aldosterone release caused by this interaction. Pomisartan results in a blood pressure-lowering effect[1].
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Pomisartan | Pomisartan is an orally active angiotensin II receptor type AT1 antagonist (IC50=0.26 μM). Pomisartan works by inhibiting the binding of angiotensin II to the AT1 receptor, thereby blocking the vasoconstriction and aldosterone release caused by this interaction. Pomisartan results in a blood pressure-lowering effect. | |||||||||||||||||||||
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