1448314-31-5
Chemical Structure
Neutrophil elastase inhibitor 1
- CAS No.: 1448314-31-5
- Formula:C16H11N3O
- Molecular Weight:261.28
IUPAC Name: 1-(3-methylbenzoyl)-1H-indazole-3-carbonitrile
InChIKey: KRFSMLDUZFVINX-UHFFFAOYSA-N
SMILES: N#CC1=NN(C2=C1C=CC=C2)C(C3=CC=CC(C)=C3)=O
Biological Activity: Neutrophil elastase inhibitor 1 is a competitive, pseudo-reversible inhibitor of human neutrophil elastase (HNE) with an IC50 of 7 nM. Neutrophil elastase inhibitor 1 also exhibits inhibitory activity against thrombin, chymotrypsin and urokinase, with IC50 values of 1.9 μM, 66 nM and 6.6 μM, respectively. Neutrophil elastase inhibitor 1 can be used in research related to acute respiratory distress syndrome, chronic obstructive pulmonary disease and other conditions[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Neutrophil elastase inhibitor 1 | 98.22% | Neutrophil elastase inhibitor 1 is a competitive, pseudo-reversible inhibitor of human neutrophil elastase (HNE) with an IC50 of 7 nM. Neutrophil elastase inhibitor 1 also exhibits inhibitory activity against thrombin, chymotrypsin and urokinase, with IC50 values of 1.9 μM, 66 nM and 6.6 μM, respectively. Neutrophil elastase inhibitor 1 can be used in research related to acute respiratory distress syndrome, chronic obstructive pulmonary disease and other conditions. | ||||||||||||||||||||
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