144909-21-7
144909-21-7
Chemical Structure
RG 14921
- CAS No.: 144909-21-7
- Formula:C11H9NO3
- Molecular Weight:203.19
IUPAC Name: 5-(2,5-dihydroxyphenyl)pyridin-2(1H)-one
InChIKey: BTJICUWFWQIODX-UHFFFAOYSA-N
SMILES: O=C1C=CC(C2=CC(O)=CC=C2O)=CN1
Biological Activity: RG 14921 is a compound structurally related to Erbstatin (HY-113549) and has inhibitory activity against EGFR tyrosine kinase and CAMP-dependent kinase activity. RG 14921 inhibits EGF receptor kinase activity as a noncompetitive inhibitor.
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RG 14921 | RG 14921 is a compound structurally related to Erbstatin (HY-113549) and has inhibitory activity against EGFR tyrosine kinase and CAMP-dependent kinase activity. RG 14921 inhibits EGF receptor kinase activity as a noncompetitive inhibitor. | |||||||||||||||||||||
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