1453084-37-1
1453084-37-1
Chemical Structure
Mirvetuximab soravtansine (solution)
Synonym(s): IMGN853 (solution)
- CAS No.: 1453084-37-1
- Formula:N/A
- Molecular Weight:150000 (average)
SMILES: [Mirvetuximab soravtansine (solution)]
Biological Activity: Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α (FRα) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A, and the drug-linker conjugate for ADC is sulfo-SPDB-DM4 (HY-101141). Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mirvetuximab soravtansine (solution) | 97.25% | Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α (FRα) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A, and the drug-linker conjugate for ADC is sulfo-SPDB-DM4 (HY-101141). Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage. | ||||||||||||||||||||
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