1453222-26-8
Chemical Structure
SAH-EZH2
- CAS No.: 1453222-26-8
- Formula:C155H256N48O40
- Molecular Weight:3431.99
InChIKey: VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES: O=C([C@]1(NC([C@@H](NC([C@](NC([C@@H](NC([C@](C)(CCC/C=C/CCC1)NC([C@H](CCCNC(N)=N)NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@H](CO)NC([C@@H](NC(C)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)CCCCN)=O)([H])[C@@H](C)CC)=O)CC(C)C)=O)C)N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N3[C@@H](CCC3)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O)=O)=O)=O)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: SAH-EZH2, a stable EZH2 α-helical peptide, is an EZH2/EED interaction inhibitor. SAH-EZH2 targets native embryonic ectoderm development (EED), disturbs its interactions with EZH1 and EZH2, and selectively decreases trimethylation of H3K27[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SAH-EZH2 | 99.50% | SAH-EZH2, a stable EZH2 α-helical peptide, is an EZH2/EED interaction inhibitor. SAH-EZH2 targets native embryonic ectoderm development (EED), disturbs its interactions with EZH1 and EZH2, and selectively decreases trimethylation of H3K27. | ||||||||||||||||||||
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