145563-68-4
145563-68-4
Chemical Structure
Rovunaptabin
Synonym(s): ARC 183; BC 007
- CAS No.: 145563-68-4
- Formula:N/A
- Molecular Weight:4726.07
IUPAC Name: 4-(fluoromethyl)-4-methylpiperidine
SMILES: DNA, d(G-G-T-T-G-G-T-G-T-G-G-T-T-G-G)
Biological Activity: Rovunaptabin (ARC 183) is an aptamer, a single-stranded DNA molecule composed of 15 deoxynucleotides. It acts as a broad-spectrum neutralizer of pathogenic G-protein-coupled receptor autoantibodies. Rovunaptabin can be used in research related to cardiomyopathy and pulmonary hypertension[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Rovunaptabin | 99.49% | Rovunaptabin (ARC 183) is an aptamer, a single-stranded DNA molecule composed of 15 deoxynucleotides. It acts as a broad-spectrum neutralizer of pathogenic G-protein-coupled receptor autoantibodies. Rovunaptabin can be used in research related to cardiomyopathy and pulmonary hypertension. | ||||||||||||||||||||
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References
- [1]. Haberland A, et al. Aptamer BC 007 - A broad spectrum neutralizer of pathogenic autoantibodies against G-protein-coupled receptors. Eur J Pharmacol. 2016;789:37-45. [Content Brief]
- [2]. Werner S, et al. The aptamer BC 007 for treatment of dilated cardiomyopathy: evaluation in Doberman Pinschers of efficacy and outcomes. ESC Heart Fail. 2020;7(3):844-855. [Content Brief]
