145767-97-1
145767-97-1
Chemical Structure
Vaniliprole
Synonym(s): MMV1794214
- CAS No.: 145767-97-1
- Formula:C20H10Cl2F6N4O2S
- Molecular Weight:555.28
IUPAC Name: (E)-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((4-hydroxy-3-methoxybenzylidene)amino)-4-((trifluoromethyl)thio)-1H-pyrazole-3-carbonitrile
InChIKey: LWWDYSLFWMWORA-BEJOPBHTSA-N
SMILES: N#CC1=NN(C2=C(C=C(C(F)(F)F)C=C2Cl)Cl)C(/N=C/C3=CC=C(C(OC)=C3)O)=C1SC(F)(F)F
Biological Activity: Vaniliprole (MMV1794214) is a phenylpyrazole compound with anti-Toxoplasma gondii activity, with an EC50 of 0.07 μM. Vaniliprole can be used in research related to parasitic infections[1][2].
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Vaniliprole | Vaniliprole (MMV1794214) is a phenylpyrazole compound with anti-Toxoplasma gondii activity, with an EC50 of 0.07 μM. Vaniliprole can be used in research related to parasitic infections. | |||||||||||||||||||||
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References
- [1]. Sun J, et al. Bis (trifluoromethylthio) carbene as a toolbox for versatile carbene transformations. Nature Communications. 2026 Jul 29.
- [2]. Zhao Q, et al. Design, synthesis and insecticidal activity of novel phenylpyrazoles containing a 2,2,2-trichloro-1-alkoxyethyl moiety. Journal of agricultural and food chemistry. 2010 Apr 28;58(8):4992-8.
