146426-20-2
146426-20-2
Chemical Structure
N6-Hydroxynorvalylcarbamoyladenosine
Synonym(s): hn6A
- CAS No.: 146426-20-2
- Formula:C16H22N6O8
- Molecular Weight:426.38
IUPAC Name: 2-(3-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)ureido)-3-hydroxypentanoic acid
InChIKey: CKYYHBNGEDJKKW-DGTGAXRRSA-N
SMILES: CCC(O)C(C(O)=O)NC(NC1=C2C(N([C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C=N2)=NC=N1)=O
Biological Activity: N6-Hydroxynorvalylcarbamoyladenosine (hn6A) (compound 1) is a nucleoside discovered in unfractionated tRNA from Thermodesulfobacterium commune[1]. N6-Hydroxynorvalylcarbamoyladenosine is a modified nucleoside[2].
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N6-Hydroxynorvalylcarbamoyladenosine | N6-Hydroxynorvalylcarbamoyladenosine (hn6A) (compound 1) is a nucleoside discovered in unfractionated tRNA from Thermodesulfobacterium commune. N6-Hydroxynorvalylcarbamoyladenosine is a modified nucleoside. | |||||||||||||||||||||
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References
- [1]. Reddy DM, et al. Structure determination of two new amino acid-containing derivatives of adenosine from tRNA of thermophilic bacteria and archaea. Nucleic Acids Res. 1992 Nov 11;20(21):5607-15. [Content Brief]
- [2]. Yun Yang, et al. Constructs and methods for preparing circular rnas and use thereof. WO2022247943. 2022-12-01.
