14667-55-1
14667-55-1
Chemical Structure
2,3,5-Trimethylpyrazine
- CAS No.: 14667-55-1
- Formula:C7H10N2
- Molecular Weight:122.17
IUPAC Name: 2,3,5-trimethylpyrazine
InChIKey: IAEGWXHKWJGQAZ-UHFFFAOYSA-N
SMILES: CC1=CN=C(C)C(C)=N1
Biological Activity: 2,3,5-Trimethylpyrazine is an activator of OR5K1 with an EC50 of 65.03 μM in Hana-3A cells. 2,3,5-Trimethylpyrazine inhibits ZEN biosynthetic gene expression, disrupts cell membrane phospholipid composition, and inhibits mycelial growth. 2,3,5-Trimethylpyrazine inhibits DNA synthesis in the chorioallantoic membrane without disrupting vascular pattern formation. 2,3,5-Trimethylpyrazine inhibits ciliary beating frequency, oocyte pickup, and infundibular smooth muscle contraction in hamster oviduct explants. 2,3,5-Trimethylpyrazine is useful for research related to plant fungal infections[1][2][3][4][5][6].
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2,3,5-Trimethylpyrazine | 99.92% | 2,3,5-Trimethylpyrazine is an activator of OR5K1 with an EC50 of 65.03 μM in Hana-3A cells. 2,3,5-Trimethylpyrazine inhibits ZEN biosynthetic gene expression, disrupts cell membrane phospholipid composition, and inhibits mycelial growth. 2,3,5-Trimethylpyrazine inhibits DNA synthesis in the chorioallantoic membrane without disrupting vascular pattern formation. 2,3,5-Trimethylpyrazine inhibits ciliary beating frequency, oocyte pickup, and infundibular smooth muscle contraction in hamster oviduct explants. 2,3,5-Trimethylpyrazine is useful for research related to plant fungal infections. | ||||||||||||||||||||
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2,3,5-Trimethylpyrazine (Standard) | ≥98% | 2,3,5-Trimethylpyrazine (Standard) is the analytical standard of 2,3,5-Trimethylpyrazine (HY-W010476). This product is intended for research and analytical applications. 2,3,5-Trimethylpyrazine is an activator of OR5K1 with an EC50 of 65.03 μM in Hana-3A cells. 2,3,5-Trimethylpyrazine inhibits ZEN biosynthetic gene expression, disrupts cell membrane phospholipid composition, and inhibits mycelial growth. 2,3,5-Trimethylpyrazine inhibits DNA synthesis in the chorioallantoic membrane without disrupting vascular pattern formation. 2,3,5-Trimethylpyrazine inhibits ciliary beating frequency, oocyte pickup, and infundibular smooth muscle contraction in hamster oviduct explants. 2,3,5-Trimethylpyrazine is useful for research related to plant fungal infections. | ||||||||||||||||||||
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2,3,5-Trimethylpyrazine-d10 | 2,3,5-Trimethylpyrazine-d10 is the deuterated-labeled 2,3,5-Trimethylpyrazine (HY-W010476). 2,3,5-Trimethylpyrazine is an activator of OR5K1 with an EC50 of 65.03 μM in Hana-3A cells. 2,3,5-Trimethylpyrazine inhibits ZEN biosynthetic gene expression, disrupts cell membrane phospholipid composition, and inhibits mycelial growth. 2,3,5-Trimethylpyrazine inhibits DNA synthesis in the chorioallantoic membrane without disrupting vascular pattern formation. 2,3,5-Trimethylpyrazine inhibits ciliary beating frequency, oocyte pickup, and infundibular smooth muscle contraction in hamster oviduct explants. 2,3,5-Trimethylpyrazine is useful for research related to plant fungal infections. | |||||||||||||||||||||
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2,3,5-Trimethylpyrazine-d3 | 2,3,5-Trimethylpyrazine-d3 is the deuterated-labeled 2,3,5-Trimethylpyrazine (HY-W010476). 2,3,5-Trimethylpyrazine is an activator of OR5K1 with an EC50 of 65.03 μM in Hana-3A cells. 2,3,5-Trimethylpyrazine inhibits ZEN biosynthetic gene expression, disrupts cell membrane phospholipid composition, and inhibits mycelial growth. 2,3,5-Trimethylpyrazine inhibits DNA synthesis in the chorioallantoic membrane without disrupting vascular pattern formation. 2,3,5-Trimethylpyrazine inhibits ciliary beating frequency, oocyte pickup, and infundibular smooth muscle contraction in hamster oviduct explants. 2,3,5-Trimethylpyrazine is useful for research related to plant fungal infections. | |||||||||||||||||||||
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2,3,5-Trimethylpyrazine-d9 | 2,3,5-Trimethylpyrazine-d9 is the deuterated-labeled 2,3,5-Trimethylpyrazine (HY-W010476). 2,3,5-Trimethylpyrazine is an activator of OR5K1 with an EC50 of 65.03 μM in Hana-3A cells. 2,3,5-Trimethylpyrazine inhibits ZEN biosynthetic gene expression, disrupts cell membrane phospholipid composition, and inhibits mycelial growth. 2,3,5-Trimethylpyrazine inhibits DNA synthesis in the chorioallantoic membrane without disrupting vascular pattern formation. 2,3,5-Trimethylpyrazine inhibits ciliary beating frequency, oocyte pickup, and infundibular smooth muscle contraction in hamster oviduct explants. 2,3,5-Trimethylpyrazine is useful for research related to plant fungal infections. | |||||||||||||||||||||
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References
- [1]. Gao Y. Comprehensive chemical characterization of Alcoholic beverages and discovery of bioactive components regulating alcohol metabolism enzyme activities. npj Science of Food. 2026 Aug 4.
- [2]. Hu B, et al. Elucidating odorant synergy in red wine: through olfactory receptor-based profiling. NPJ science of food. 2026 Mar 14;10(1):141.
- [3]. Huang H. Bacterial pyrazine volatiles: A novel approach to inhibit Fusarium graminearum growth and mycotoxin production. Food Bioscience. 2025 Mar 1;65:106059.
- [4]. Osada K, et al. Structure-Activity Relationships of Alkylpyrazine Analogs and Fear-Associated Behaviors in Mice. Journal of chemical ecology. 2017 Mar;43(3):263-272.
- [5]. Melkonian G, et al. Growth and angiogenesis are inhibited in vivo in developing tissues by pyrazine and its derivatives. Toxicological sciences : an official journal of the Society of Toxicology. 2003 Oct;75(2):393-401.
- [6]. Riveles K, et al. Pyrazine derivatives in cigarette smoke inhibit hamster oviductal functioning. Reproductive biology and endocrinology : RB&E. 2004 May 12;2:23.
