1467059-70-6
1467059-70-6
Chemical Structure
PF-06685249
Synonym(s): PF-249
- CAS No.: 1467059-70-6
- Formula:C17H16ClN3O3
- Molecular Weight:345.78
IUPAC Name: 6-chloro-5-(6-(dimethylamino)-2-methoxypyridin-3-yl)-1H-indole-3-carboxylic acid
InChIKey: MJHBRTGGZYSCHJ-UHFFFAOYSA-N
SMILES: O=C(C1=CNC2=C1C=C(C3=CC=C(N(C)C)N=C3OC)C(Cl)=C2)O
Biological Activity: PF-06685249 (PF-249) is a potent and orally active allosteric AMPK activator with an EC50 of 12 nM for recombinant AMPK α1β1γ1. PF-06685249 improves renal function in ZSF-1 rats with diabetic nephropathy. PF-06685249 can be used for diabetic nephropathy research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-06685249 | 98.00% | PF-06685249 (PF-249) is a potent and orally active allosteric AMPK activator with an EC50 of 12 nM for recombinant AMPK α1β1γ1. PF-06685249 improves renal function in ZSF-1 rats with diabetic nephropathy. PF-06685249 can be used for diabetic nephropathy research. | ||||||||||||||||||||
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