146739-86-8
Chemical Structure
S-2720
- CAS No.: 146739-86-8
- Formula:C14H15ClN2O2S
- Molecular Weight:310.80
IUPAC Name: prop-1-en-2-yl 7-chloro-2,2-dimethyl-3-thioxo-3,4-dihydroquinoxaline-1(2H)-carboxylate
InChIKey: UNOJVGJCKUQAGH-UHFFFAOYSA-N
SMILES: O=C(N1C2=CC(Cl)=CC=C2NC(C1(C)C)=S)OC(C)=C
Biological Activity: S-2720 is a potent inhibitor of both immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) and HIV-1 replication. The binding sites of S-2720 and the nonnucleoside compounds overlap. The small pocket in the p66 subunit-BI-RG-587 (HY-10570) complex is most likely the target of S-2720. S-2720 is a quinoxaline derivative, which is promising for research of HIV-1 infection[1].
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S-2720 | S-2720 is a potent inhibitor of both immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) and HIV-1 replication. The binding sites of S-2720 and the nonnucleoside compounds overlap. The small pocket in the p66 subunit-BI-RG-587 (HY-10570) complex is most likely the target of S-2720. S-2720 is a quinoxaline derivative, which is promising for research of HIV-1 infection. | |||||||||||||||||||||
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