146957-32-6
146957-32-6
Chemical Structure
Moxilubant hydrochloride
Synonym(s): CGS 25019C hydrochloride
- CAS No.: 146957-32-6
- Formula:C26H38ClN3O4
- Molecular Weight:492.05
InChIKey: KGGKWACNSRKUGL-UHFFFAOYSA-N
SMILES: [H]Cl.CC(C)N(C(C)C)C(C1=CC(OC)=C(OCCCCCOC2=CC=C(C(N)=N)C=C2)C=C1)=O
Biological Activity: Moxilubant (CGS 25019C) hydrochloride is an orally active BLT1 antagonist. Moxilubant hydrochloride inhibits LTB4 signaling with a potency of 2-4 nM. Moxilubant hydrochloride blocks LTB4-induced neutrophil functions. Moxilubant hydrochloride inhibits ear edema and neutrophil infiltration in mice. Moxilubant hydrochloride can be used in research related to chronic obstructive pulmonary disease[1][2].
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Moxilubant hydrochloride | Moxilubant (CGS 25019C) hydrochloride is an orally active BLT1 antagonist. Moxilubant hydrochloride inhibits LTB4 signaling with a potency of 2-4 nM. Moxilubant hydrochloride blocks LTB4-induced neutrophil functions. Moxilubant hydrochloride inhibits ear edema and neutrophil infiltration in mice. Moxilubant hydrochloride can be used in research related to chronic obstructive pulmonary disease. | |||||||||||||||||||||
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