1476847-58-1
1476847-58-1
Chemical Structure
VU0652925
- CAS No.: 1476847-58-1
- Formula:C24H18N4O4S2
- Molecular Weight:490.55
IUPAC Name: 2-methoxy-6-(6-methoxy-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole
InChIKey: RROGCGMHOWNSLD-UHFFFAOYSA-N
SMILES: COC1=NN2C(S1)=NC(C3=CC4=C(C=C(C=C4OCC5=CSC(C6=CC=CC=C6)=N5)OC)O3)=C2
Biological Activity: VU0652925, an analog of BMS986120, is a PAR4 antagonist, with IC50 values of 43 pM and 39.2 pM for PAC1 and P-selectin, respectively. VU0652925 is able to suppress GPIIbIIIa activation[1].
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VU0652925 | VU0652925, an analog of BMS986120, is a PAR4 antagonist, with IC50 values of 43 pM and 39.2 pM for PAC1 and P-selectin, respectively. VU0652925 is able to suppress GPIIbIIIa activation. | |||||||||||||||||||||
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