14772-95-3
14772-95-3
Chemical Structure
3-Oxo-7-hydroxychol-4-enoic acid
- CAS No.: 14772-95-3
- Formula:C24H36O4
- Molecular Weight:388.54
IUPAC Name: (R)-4-((7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
InChIKey: CFLVYJJIZHNITM-NLXMLWGDSA-N
SMILES: C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H]3O)=CC(CC4)=O)C
Biological Activity: 3-Oxo-7-hydroxychol-4-enoic acid is an endogenous metabolite. 3-Oxo-7-hydroxychol-4-enoic acid may be an important indicator of a poor prognosis in hepatobiliary disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Oxo-7-hydroxychol-4-enoic acid | 98.60% | 3-Oxo-7-hydroxychol-4-enoic acid is an endogenous metabolite. 3-Oxo-7-hydroxychol-4-enoic acid may be an important indicator of a poor prognosis in hepatobiliary disease. | ||||||||||||||||||||
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3-Oxo-7-hydroxychol-4-enoic acid (Standard) | ≥98% | 3-Oxo-7-hydroxychol-4-enoic acid is an endogenous metabolite. 3-Oxo-7-hydroxychol-4-enoic acid may be an important indicator of a poor prognosis in hepatobiliary disease. | ||||||||||||||||||||
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7α-Hydroxy-4-cholesten-3-one (Standard) | ≥98% | 7α-Hydroxy-4-cholesten-3-one (Standard) is the analytical standard of 7α-Hydroxy-4-cholesten-3-one. This product is intended for research and analytical applications. 7α-Hydroxy-4-cholesten-3-one is an intermediate in synthesis of bile acids from cholesterol. 7α-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7α-Hydroxy-cholest-4-en-3-one is the physiological substrate for CYP8B1. | ||||||||||||||||||||
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3b-Hydroxy-5-cholenoic acid (Standard) | ≥98% | 3b-Hydroxy-5-cholenoic acid (Standard) is an analytical standard for 3b-Hydroxy-5-cholenoic acid. This product is intended for research and analytical applications. 3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin. 3b-Hydroxy-5-cholenoic acid can be used in the study of hepatic ductular hypoplasia syndrome. | ||||||||||||||||||||
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(3β)-3-Hydroxy-7-oxochol-5-en-24-oic acid | (3β)-3-Hydroxy-7-oxochol-5-en-24-oic acid is a bile acid, and is a metabolite of 7β-hydroxy cholesterol (HY-113341). | |||||||||||||||||||||
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(7α,24S)-7,24-Dihydroxycholest-4-en-3-one | (7α,24S)-7,24-Dihydroxycholest-4-en-3-one is an oxysterol. | |||||||||||||||||||||
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3-Oxochol-5-en-24-oic acid | 3-Oxochol-5-en-24-oic acid is a rare bile acid produced by the intestinal microbiota. 3-Oxochol-5-en-24-oic acid is a potent antagonist of the human androgen receptor (hAR), with an IC50 of 119.4 nM. 3-Oxochol-5-en-24-oic acid has no significant agonistic or antagonistic effects on estrogen receptors (ER) or glucocorticoid receptors (GR). 3-Oxochol-5-en-24-oic acid effectively inhibits the growth of prostate cancer cells. In animal models, it enhances the efficacy of anti-PD-1 therapy by regulating the differentiation of CD8+ T cells. 3-Oxochol-5-en-24-oic acid can be used for research on regulating host immunity and anti-tumor studies. | |||||||||||||||||||||
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7α,25-Dihydroxy-4-cholesten-3-one | 7α,25-Dihydroxy-4-cholesten-3-one is a sterol metabolite. 25-Hydroxycholesterol is 7α-hydroxylated and further oxidized to 7α,25-Dihydroxy-4-cholesten-3-one. | |||||||||||||||||||||
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4-Cholenic acid-3-one | 4-Cholenic acid-3-one is an antifeedant steroid metabolite formed via anaerobic biotransformation of Lithocholic acid (HY-B0172) by Pseudomonas sp. strain NCIB 10590. | |||||||||||||||||||||
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7α,27-Dihydroxy-4-cholesten-3-one | 7α,27-Dihydroxy-4-cholesten-3-one is an oxysterol. | |||||||||||||||||||||
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7-Hydroxy-3-oxo-Cholest-4-en-26-oic acid | 98.18% | 7-Hydroxy-3-oxo-cholest-4-en-26-oic acid is a steroid carboxylic acid that plays an important role in the biosynthesis of bile acids. | ||||||||||||||||||||
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Cholesterol impurity 4 | Cholesterol impurity 4 is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery. | |||||||||||||||||||||
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