148905-79-7
148905-79-7
Chemical Structure
LY300503
- CAS No.: 148905-79-7
- Formula:C14H16ClNO
- Molecular Weight:249.74
IUPAC Name: (4aS,10bS)-8-chloro-4-methyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one
InChIKey: WQBIOEFDDDEARX-STQMWFEESA-N
SMILES: CN1[C@]2([H])[C@](CCC1=O)([H])C3=CC=C(Cl)C=C3CC2
Biological Activity: LY300503 is an enantiomer of LY191704. LY191704 is a human type I 5α-reductase inhibitor[1][2].
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LY300503 | LY300503 is an enantiomer of LY191704. LY191704 is a human type I 5α-reductase inhibitor. | |||||||||||||||||||||
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References
- [1]. Farid NA, et, al. High-performance liquid chromatographic determination of the enantiomers of the benzoquinolinone LY191704, a human type 1 5 alpha-reductase inhibitor, in plasma. J Chromatogr B Biomed Sci Appl. [Content Brief]
- [2]. Farid NA, et, al. Stereoselective disposition of the enantiomers of the benzoquinolinone LY191704, a human type I 5 alpha-reductase inhibitor. Differences between rats and dogs. Drug Metab Dispos. 1996 Oct;24(10):1162-5. [Content Brief]
