149437-51-4
149437-51-4
Chemical Structure
LTD4 antagonist 3
Synonym(s): FK011 hydrochloride
- CAS No.: 149437-51-4
- Formula:C24H24ClNO4S
- Molecular Weight:457.97
IUPAC Name: 2-(2-(((2-(4-(tert-butyl)thiazol-2-yl)benzofuran-5-yl)oxy)methyl)phenyl)acetic acid hydrochloride
InChIKey: UXBRVGLLTFHRME-UHFFFAOYSA-N
SMILES: O=C(CC1=C(COC2=CC3=C(OC(C4=NC(C(C)(C)C)=CS4)=C3)C=C2)C=CC=C1)O.Cl
Biological Activity: LTD4 antagonist 3 (FK011 hydrochloride) is a LTD4 antagonist. LTD4 antagonist 3 has agonistic activity for PPAR-γ, with a fold-increase of 1.50 at 1 μM and 2.35 at 10 μM. LTD4 antagonist 3 can be used of development of non-steroidal anti-inflammatory drugs (NSAIDs)[1].
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LTD4 antagonist 3 | LTD4 antagonist 3 (FK011 hydrochloride) is a LTD4 antagonist. LTD4 antagonist 3 has agonistic activity for PPAR-γ, with a fold-increase of 1.50 at 1 μM and 2.35 at 10 μM. LTD4 antagonist 3 can be used of development of non-steroidal anti-inflammatory drugs (NSAIDs). | |||||||||||||||||||||
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