149719-06-2
149719-06-2
Chemical Structure
RS 23597-190
Synonym(s): EP-A-501322
- CAS No.: 149719-06-2
- Formula:C16H24Cl2N2O3
- Molecular Weight:363.28
IUPAC Name: 3-(piperidin-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride
InChIKey: QLZLBYYNMGQIAR-UHFFFAOYSA-N
SMILES: O=C(OCCCN1CCCCC1)C2=CC(Cl)=C(N)C=C2OC.Cl
Biological Activity: RS 23597-190 (EP-A-501322) is a high affinity and selective 5-HT4 receptor antagonist. RS 23597-190 inhibits Serotonin (HY-B1473A)-induced tachycardia. RS 23597-190 significantly inhibits superoxide production in high glucose[1][2].
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RS 23597-190 | 99.81% | RS 23597-190 (EP-A-501322) is a high affinity and selective 5-HT4 receptor antagonist. RS 23597-190 inhibits Serotonin (HY-B1473A)-induced tachycardia. RS 23597-190 significantly inhibits superoxide production in high glucose. | ||||||||||||||||||||
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RS 23597-190 (Standard) | ≥98% | RS 23597-190 (Standard) is the analytical standard of RS 23597-190 (HY-101172). This product is intended for research and analytical applications. RS 23597-190 (EP-A-501322) is a high affinity and selective 5-HT4 receptor antagonist. RS 23597-190 inhibits Serotonin (HY-B1473A)-induced tachycardia. RS 23597-190 significantly inhibits superoxide production in high glucose. | ||||||||||||||||||||
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References
- [1]. Eglen RM, et al. RS 23597-190: a potent and selective 5-HT4 receptor antagonist. Br J Pharmacol. 1993 Sep;110(1):119-26. [Content Brief]
- [2]. Du Y, et al. Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability. FASEB J. 2015 May;29(5):2194-204. [Content Brief]
