149759-96-6
149759-96-6
Chemical Structure
Ftase inhibitor I
Synonym(s): B581
- CAS No.: 149759-96-6
- Formula:C22H38N4O3S2
- Molecular Weight:470.69
IUPAC Name: ((S)-2-(((R)-2-amino-3-mercaptopropyl)amino)-3-methylbutyl)-L-phenylalanyl-L-methionine
InChIKey: QISLMXIYRQCLIR-FUMNGEBKSA-N
SMILES: CSCC[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC[C@@H](NC[C@@H](N)CS)C(C)C)=O
Biological Activity: Ftase inhibitor I (B581) is a potent, selective and peptidomimetic farnesyl transferase (FTase) inhibitor. Ftase inhibitor I shows selectivity for FTase over geranylgeranyl isoprenoid (Ras-GG) or the fatty acid myristate (Myr-Ras)[1].
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Ftase inhibitor I | Ftase inhibitor I (B581) is a potent, selective and peptidomimetic farnesyl transferase (FTase) inhibitor. Ftase inhibitor I shows selectivity for FTase over geranylgeranyl isoprenoid (Ras-GG) or the fatty acid myristate (Myr-Ras). | |||||||||||||||||||||
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