1498300-31-4
1498300-31-4
Chemical Structure
TNKS1/2-IN-1
- CAS No.: 1498300-31-4
- Formula:C26H23F4N3O4
- Molecular Weight:517.47
IUPAC Name: (1r,4r)-4-((1-(2-cyano-3-(trifluoromethyl)benzyl)-6-fluoro-5-methyl-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)methyl)cyclohexane-1-carboxylic acid
InChIKey: UEPQJCJZMGAYPN-WKILWMFISA-N
SMILES: O=C(N1C[C@H]2CC[C@H](C(O)=O)CC2)N(CC3=CC=CC(C(F)(F)F)=C3C#N)C4=CC=C(F)C(C)=C4C1=O
Biological Activity: TNKS1/2-IN-1 (Example 4) is a TNKS1 and TNKS2 inhibitor, with pIC50 values of 8.2 or 7.3 against TNKS1, and 7.1 or 7.7 against TNKS2. TNKS1/2-IN-1 inhibits the enzymatic activities of TNKS1 and TNKS2. TNKS1/2-IN-1 is applicable for cancer research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
TNKS1/2-IN-1 | 99.24% | TNKS1/2-IN-1 (Example 4) is a TNKS1 and TNKS2 inhibitor, with pIC50 values of 8.2 or 7.3 against TNKS1, and 7.1 or 7.7 against TNKS2. TNKS1/2-IN-1 inhibits the enzymatic activities of TNKS1 and TNKS2. TNKS1/2-IN-1 is applicable for cancer research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
