1501618-04-7
1501618-04-7
Chemical Structure
EIF2α activator 2
- CAS No.: 1501618-04-7
- Formula:C21H20F6N2O2
- Molecular Weight:446.39
IUPAC Name: 1-((1r,4r)-4-(4-(trifluoromethyl)phenoxy)cyclohexyl)-3-(3-(trifluoromethyl)phenyl)urea
InChIKey: MFRDVPYKJUYMDN-RZDIXWSQSA-N
SMILES: FC(F)(F)C(C=C1)=CC=C1O[C@H](CC2)CC[C@@H]2NC(NC3=CC(C(F)(F)F)=CC=C3)=O
Biological Activity: EIF2α activator 2 (Compound 1) is an activator of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation. EIF2α activator 2 exhibits high potency in SRB cell proliferation assays (IC50=0.46 μM). EIF2α activator 2 exhibits antiproliferative activity againist K562 and PBMC cells with IC50s of 4.79 and 10.52 μM, respectively[1].
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EIF2α activator 2 | 99.57% | EIF2α activator 2 (Compound 1) is an activator of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation. EIF2α activator 2 exhibits high potency in SRB cell proliferation assays (IC50=0.46 μM). EIF2α activator 2 exhibits antiproliferative activity againist K562 and PBMC cells with IC50s of 4.79 and 10.52 μM, respectively. | ||||||||||||||||||||
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