150322-05-7
150322-05-7
Chemical Structure
5-Carboxytetramethylrhodamine
- CAS No.: 150322-05-7
- Formula:C25H22N2O5
- Molecular Weight:430.45
IUPAC Name: 3',6'-bis(dimethylamino)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxylic acid
InChIKey: DCVXPZDNLDPUES-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(C3(C4=C(OC5=C3C=CC(N(C)C)=C5)C=C(N(C)C)C=C4)OC2=O)C=C1)O
Biological Activity: 5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5-Carboxytetramethylrhodamine | 98.85% | 5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm. | ||||||||||||||||||||
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6-FAM | 99.72% | 6-FAM (6-Carboxyfluorescein) is an isomer of carboxyfluorescein and is mainly used for sequencing and labeling of nucleic acids. | ||||||||||||||||||||
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5-FAM | 99.58% | 5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm. | ||||||||||||||||||||
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5-CFDA | 98.22% | 5-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes. | ||||||||||||||||||||
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NHS-5(6)Carboxyrhodamine | NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions. | |||||||||||||||||||||
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Rhodamine B base | 97.0% | Rhodamine B base (Solvent red 49) is a fluorescent dye (Ex=543 nM; Em=565 nM). | ||||||||||||||||||||
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Mordant red 15 | Mordant red 15 is an azo dye commonly used for dyeing textiles. | |||||||||||||||||||||
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N,N'-Bis[2-(acetamido)ethyl]-N,N'-dimethyl rhodamine | N,N'-Bis[2-(acetamido)ethyl]-N,N'-dimethyl rhodamine is a fluorescent reagent. | |||||||||||||||||||||
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5-TAMRA-NHS | 5-TAMRA-NHS is a fluorescent dye composed of 5-TAMRA (HY-15942) and a hydroxysuccinimide (NHS) group. The NHS ester of 5-TAMRA-NHS forms amide bonds with primary amino groups, which is used to construct fluorescently labeled probes and conjugates. The labeled products are suitable for fluorescence anisotropy, confocal imaging and flow cytometry assays. 5-TAMRA-NHS can be used for fluorescent labeling and imaging (Ex/Em = 541/567 nm). | |||||||||||||||||||||
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6-TAMRA free acid | 97.0% | 6-TAMRA free acid is a fluorophore widely used in the preparation of fluorescent antibodies and avidin derivatives for immunohistochemistry. | ||||||||||||||||||||
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TAMRA-PEG2-Maleimide | 95.0% | TAMRA-PEG2-Maleimide is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond. | ||||||||||||||||||||
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References
- [1]. Lyu Z, et al. Steric-Free Bioorthogonal Labeling of Acetylation Substrates Based on a Fluorine-Thiol Displacement Reaction. J Am Chem Soc. 2021 Jan 27;143(3):1341-1347. [Content Brief]
- [2]. Bucevičius J, et al. Rhodamine-Hoechst positional isomers for highly efficient staining of heterochromatin. Chem Sci. 2018 Dec 12;10(7):1962-1970. [Content Brief]
- [3]. Lyttle MH, et al. A tetramethyl rhodamine (Tamra) phosphoramidite facilitates solid-phase-supported synthesis of 5'-Tamra DNA. J Org Chem. 2000 Dec 29;65(26):9033-8. [Content Brief]
