150956-50-6
150956-50-6
Chemical Structure
Canventol
- CAS No.: 150956-50-6
- Formula:C12H20O
- Molecular Weight:180.29
InChIKey: CYOJESZRZNCQEV-UHFFFAOYSA-N
SMILES: OC1C(C(C)C)=C/C(CC1)=C(C)\C
Biological Activity: Canventol is an antitumor agent that inhibits the release of TNF-α. Canventol inhibits protein isoprenylation, regulates mevalonate metabolism, enhances Okadaic acid (HY-N6785)-induced early response gene expression, suppresses cell transformation, and inhibits HIV-1 production in infected cells. Canventol can be used in studies related to skin tumor promotion and cancer[1][2][3].
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Canventol | Canventol is an antitumor agent that inhibits the release of TNF-α. Canventol inhibits protein isoprenylation, regulates mevalonate metabolism, enhances Okadaic acid (HY-N6785)-induced early response gene expression, suppresses cell transformation, and inhibits HIV-1 production in infected cells. Canventol can be used in studies related to skin tumor promotion and cancer. | |||||||||||||||||||||
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References
- [1]. Komori A, et al. Canventol inhibits tumor promotion in CD-1 mouse skin through inhibition of tumor necrosis factor alpha release and of protein isoprenylation. Cancer research. 1993 Aug 01;53(15):3462-4. [Content Brief]
- [2]. Suganuma M, Okabe S, Sueoka E, Iida N, Komori A, Kim SJ, Fujiki H. A new process of cancer prevention mediated through inhibition of tumor necrosis factor α expression. Cancer Res. 1996;56:3711-3715. [Content Brief]
- [3]. Komori A, et al. Anti-tumor promoting activity of canventol and its synthetic analogs through inhibition of protein isoprenylation. Japanese journal of cancer research : Gann. 1996 Sep;87(9):875-81. [Content Brief]
