151201-76-2
151201-76-2
Chemical Structure
Astin B
- CAS No.: 151201-76-2
- Formula:C25H33Cl2N5O7
- Molecular Weight:586.46
InChIKey: DQILVZOWLYBPKT-UHFFFAOYSA-N
SMILES: Cl[C@H](C1)[C@@H](Cl)[C@@](N1C([C@H](CC)NC(C[C@H](C2=CC=CC=C2)N3)=O)=O)([H])C(N[C@H]([C@H](C)O)C(N[C@@H](CO)C3=O)=O)=O
Biological Activity: Astin B is a orally active and potent cyclic pentapeptide, that can be isolated from Aster tataricus. Astin B has hepatotoxic effects in vitro and in vivo and that hepatic injury was primarily mediated by apoptosis in a mitochondria/caspase-dependent manner. Astin B induces autophagy in L-02 cells, increases LC3-II and decreases p62 expression[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Astin B | 95.0% | Astin B is a orally active and potent cyclic pentapeptide, that can be isolated from Aster tataricus. Astin B has hepatotoxic effects in vitro and in vivo and that hepatic injury was primarily mediated by apoptosis in a mitochondria/caspase-dependent manner. Astin B induces autophagy in L-02 cells, increases LC3-II and decreases p62 expression. | ||||||||||||||||||||
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