151213-16-0
Chemical Structure
BAY-Y 3118
- CAS No.: 151213-16-0
- Formula:C20H21ClFN3O3
- Molecular Weight:405.85
IUPAC Name: 8-chloro-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
InChIKey: VRXORHRXNRJZCQ-ZUZCIYMTSA-N
SMILES: O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N(C4)C[C@]5([H])[C@@]4([H])CCCN5)=C3Cl)C1=O)O
Biological Activity: BAY-Y 3118 is a quinolone antibacterial agent. BAY-Y 3118 has a broad antibacterial spectrum in vitro. BAY-Y 3118 exhibits high activity against gram-positive cocci and anaerobes. BAY-Y 3118 shows moderate activity against Enterobacteriaceae and Pseudomonas aeruginosa. BAY-Y 3118 can be used in the research of infectious diseases[1][2][3].
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BAY-Y 3118 | 99.22% | BAY-Y 3118 is a quinolone antibacterial agent. BAY-Y 3118 has a broad antibacterial spectrum in vitro. BAY-Y 3118 exhibits high activity against gram-positive cocci and anaerobes. BAY-Y 3118 shows moderate activity against Enterobacteriaceae and Pseudomonas aeruginosa. BAY-Y 3118 can be used in the research of infectious diseases. | ||||||||||||||||||||
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Moxifloxacin | 99.75% | Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia. | ||||||||||||||||||||
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(Rac)-Moxifloxacin | 99.51% | (Rac)-Moxifloxacin ((Rac)-BAY 12-8039 free base) is the isoform of Moxifloxacin Hydrochloride (HY-66011), which is an oral 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia. | ||||||||||||||||||||
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Moxifloxacin Hydrochloride (Standard) | ≥98% | Moxifloxacin (Hydrochloride) (Standard) is the analytical standard of Moxifloxacin (Hydrochloride). This product is intended for research and analytical applications. Moxifloxacin Hydrochloride (BAY 12-8039) is an oral 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia. | ||||||||||||||||||||
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BAY-Y 3118 hydrochloride | BAY-Y 3118 hydrochloride is a quinolone antibacterial agent. BAY-Y 3118 hydrochloride has a broad antibacterial spectrum in vitro. BAY-Y 3118 hydrochloride exhibits high activity against gram-positive cocci and anaerobes. BAY-Y 3118 hydrochloride shows moderate activity against Enterobacteriaceae and Pseudomonas aeruginosa. BAY-Y 3118 hydrochloride can be used in the research of infectious diseases. | |||||||||||||||||||||
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(R,R)-BAY-Y 3118 | 99.57% | (R,R)-BAY-Y 3118 is the R-enantiomer of BAY-Y 3118. (R,R)-BAY-Y 3118 shows weak bactericidal activity. | ||||||||||||||||||||
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8-Desmethoxy-8-fluoro Moxifloxacin | 98.74% | 8-Desmethoxy-8-fluoro Moxifloxacin (Compound 07) is an antibacterial agent, and has bactericidal activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis. | ||||||||||||||||||||
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Moxifloxacin impurity 6 hydrobromide | Moxifloxacin impurity 6 hydrobromide (8-Hydroxymoxifloxacin hydrobromide) is an impurity of Moxifloxacin hydrobromide. | |||||||||||||||||||||
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Pradofloxacin | 98.02% | Pradofloxacin, a third-generation fluoroquinolone antibacterial agent. Pradofloxacin can be used for the study of bacterial infections in the dog and cat, such as skin infections. | ||||||||||||||||||||
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Moxifloxacin impurity 9 | Moxifloxacin impurity 9 is an impurity of Moxifloxacin. | |||||||||||||||||||||
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Moxifloxacin impurity 6 | Moxifloxacin impurity 6 (8-Hydroxymoxifloxacin) is an impurity of Moxifloxacin. | |||||||||||||||||||||
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References
- [1]. Fass RJ, et al. In vitro activity of Bay y 3118, a new quinolone. Antimicrob Agents Chemother. 1993 Nov;37(11):2348-57. [Content Brief]
- [2]. García I, et al. Intracellular penetration and activity of BAY Y 3118 in human polymorphonuclear leukocytes. Antimicrob Agents Chemother. 1994 Oct;38(10):2426-9. [Content Brief]
- [3]. Nichterlein T, et al. Bay Y 3118, a new quinolone derivative, rapidly eradicates Listeria monocytogenes from infected mice and L929 cells. Antimicrob Agents Chemother. 1994 Jul;38(7):1501-6. [Content Brief]