1513-65-1
Chemical Structure
2,6-Difluoropyridine
- CAS No.: 1513-65-1
- Formula:C5H3F2N
- Molecular Weight:115.08
IUPAC Name: 2,6-difluoropyridine
InChIKey: MBTGBRYMJKYYOE-UHFFFAOYSA-N
SMILES: FC1=CC=CC(F)=N1
Biological Activity: 2,6-Difluoropyridine is a fluorinated pyridine derivative. 2,6-Difluoropyridine adopts a planar conformation in its S0 electronic ground state and S1(π,π) excited state[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2,6-Difluoropyridine | 99.98% | 2,6-Difluoropyridine is a fluorinated pyridine derivative. 2,6-Difluoropyridine adopts a planar conformation in its S0 electronic ground state and S1(π,π) excited state. | ||||||||||||||||||||
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4-Bromo-2-fluoropyridine | 99.88% | 4-Bromo-2-fluoropyridine is a drug intermediate. | ||||||||||||||||||||
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5-Bromo-2-fluoropyridine | 99.60% | 5-Bromo-2-fluoropyridine is a halogenated pyridine precursor. 5-Bromo-2-fluoropyridine participates in Li-Br exchange to generate a pyridyl zinc halide for Negishi cross-coupling in the synthesis of nicotinic acetylcholine receptor agonist analogues. | ||||||||||||||||||||
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2-Bromo-5-fluoropyridine | 99.46% | 2-Bromo-5-fluoropyridine acts as a bromofluoropyridine starting material and an azaaryl halide coupling partner. 2-Bromo-5-fluoropyridine participates in an oxygen-promoted, ligand-free Pd (OAc)2-catalyzed Suzuki reaction, reacting with arylboronic acids to produce 5-fluoro-2-aryl-substituted pyridine derivatives. 2-Bromo-5-fluoropyridine can be used to synthesize 5-fluoro-2-(4-(methylsulfonyl) phenyl) pyridine, an intermediate of the GPR119 agonist GSK1292263A. | ||||||||||||||||||||
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2,6-Dibromopyridine | 99.62% | 2,6-Dibromopyridine is a drug intermediate that can be used for the synthesis of IRK-4 inhibitors. | ||||||||||||||||||||
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5-Amino-2-fluoropyridine | 99.89% | 5-Amino-2-fluoropyridine is a fluorinated heterocyclic compound, which can be used for the synthesis of other active compounds. | ||||||||||||||||||||
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2-Bromo-1,4-difluorobenzene | 99.97% | 2-Bromo-1,4-difluorobenzene is a fluorine-substituted haloarene and serves as an inexpensive, large-volume organic synthesis raw material. 2-Bromo-1,4-difluorobenzene can be used to prepare 1,4-difluoroanthraquinone, which is a precursor of Ametantrone (HY-13550). 2-Bromo-1,4-difluorobenzene can be used as a biomaterial or organic compound in life science-related research. | ||||||||||||||||||||
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2-Amino-6-fluoropyridine | 99.70% | 2-Amino-6-fluoropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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2-Fluoro-5-iodopyridine | 99.87% | 2-Fluoro-5-iodopyridine is an electrolyte additive. 2-Fluoro-5-iodopyridine can not only effectively protect the anode by forming a stable SEI film, but also convert dead lithium into active lithium. 2-Fluoro-5-iodopyridine effectively improves the performance of lithium metal batteries. | ||||||||||||||||||||
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3,4-Difluoroaniline (Standard) | ≥98% | 3,4-Difluoroaniline (Standard) is the analytical standard of 3,4-Difluoroaniline. This product is intended for research and analytical applications. | ||||||||||||||||||||
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2,6-Diaminopyridine | 99.96% | 2,6-Diaminopyridine is an intermediate and coupling agent for hair dyes. 2,6-Diaminopyridine participates in organic synthesis reactions such as N-methylation and can bind metal ions by forming macrocyclic ligands through condensation with aldehydes. 2,6-Diaminopyridine can be used to synthesize the analgesic phenazopyridine hydrochloride (HY-B0985). | ||||||||||||||||||||
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References
- [1]. Sheu HL, et al. Infrared, Raman, and ultraviolet absorption spectra and theoretical calculations and structure of 2,6-difluoropyridine in its ground and excited electronic states. J Phys Chem A. 2013;117(50):13596-13604. [Content Brief]
- [2]. Baiardi A, et al. Vibrationally resolved NEXAFS at C and N K-edges of pyridine, 2-fluoropyridine and 2,6-difluoropyridine: A combined experimental and theoretical assessment. J Chem Phys. 2015 Nov 28;143(20):204102. [Content Brief]