151425-92-2
151425-92-2
Chemical Structure
TRK-530 sodium
- CAS No.: 151425-92-2
- Formula:C8H10Na2O6P2S2
- Molecular Weight:374.22
IUPAC Name: sodium (((4-(methylthio)phenyl)thio)methylene)bis(hydrogen phosphonate)
InChIKey: RYDCOWIKNMACJO-UHFFFAOYSA-L
SMILES: CSC1=CC=C(SC(P(O)(O[Na])=O)P(O)(O[Na])=O)C=C1
Biological Activity: TRK-530 sodium is an orally active bisphosphonate. TRK-530 sodium inhibits CINC-1. TRK-530 sodium inhibits dental calculus formation. TRK-530 sodium also inhibits paw edema, joint destruction and osteomyelitis[1][2].
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TRK-530 sodium | TRK-530 sodium is an orally active bisphosphonate. TRK-530 sodium inhibits CINC-1. TRK-530 sodium inhibits dental calculus formation. TRK-530 sodium also inhibits paw edema, joint destruction and osteomyelitis. | |||||||||||||||||||||
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References
- [1]. Sikder MN, et al. Inhibitory effect of a novel bisphosphonate, TRK-530, on dental calculus formation in rats. J Periodontol. 2004 Apr;75(4):537-45. [Content Brief]
- [2]. Tanahashi M, et al. Inhibitory effect of TRK-530 on inflammatory cytokines in bone marrow of rats with adjuvant arthritis. Pharmacology. 1998 May;56(5):237-41. [Content Brief]
