1517780-59-4
1517780-59-4
Chemical Structure
Ferroptosis-IN-6
- CAS No.: 1517780-59-4
- Formula:C15H17NO
- Molecular Weight:227.30
InChIKey: DPIILYUBOSNTOP-UHFFFAOYSA-N
SMILES: OC1=C(C)C=CC=C1NCC2=CC=C(C)C=C2
Biological Activity: Ferroptosis-IN-6 is a potent Ferroptosis inhibitor with an EC50 of 25.5 nM. Ferroptosis-IN-6 acts as a radical-trapping antioxidant, relying on the synergistic effect of ortho-hydroxyamine to specifically block lethal lipid ROS accumulation without affecting iron homeostasis and ROS generation pathways. Ferroptosis-IN-6 can be used for research on renal ischemia-reperfusion injury[1].
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Ferroptosis-IN-6 | Ferroptosis-IN-6 is a potent Ferroptosis inhibitor with an EC50 of 25.5 nM. Ferroptosis-IN-6 acts as a radical-trapping antioxidant, relying on the synergistic effect of ortho-hydroxyamine to specifically block lethal lipid ROS accumulation without affecting iron homeostasis and ROS generation pathways. Ferroptosis-IN-6 can be used for research on renal ischemia-reperfusion injury. | |||||||||||||||||||||
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