1518800-29-7
Chemical Structure
Afabicin disodium
Synonym(s): Debio 1450 disodium; AFN-1720 disodium
- CAS No.: 1518800-29-7
- Formula:C23H22N3Na2O7P
- Molecular Weight:529.39
IUPAC Name: sodium (E)-(6-(3-(methyl((3-methylbenzofuran-2-yl)methyl)amino)-3-oxoprop-1-en-1-yl)-2-oxo-3,4-dihydro-1,8-naphthyridin-1(2H)-yl)methyl phosphate
InChIKey: ZAWLQRSRUJJWHT-OJYIHNBOSA-L
SMILES: O=P(O[Na])(O[Na])OCN1C2=NC=C(/C=C/C(N(C)CC(OC3=CC=CC=C43)=C4C)=O)C=C2CCC1=O
Biological Activity: Afabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci[1].
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Afabicin disodium | Afabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci. | |||||||||||||||||||||
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