1534358-79-6

COH000 Chemical Structure
1534358-79-6

Chemical Structure

COH000

  • CAS No.: 1534358-79-6
  • Formula:C25H25NO5
  • Molecular Weight:419.47

IUPAC Name: dimethyl (1R,4S)-1-((R)-1-(phenylamino)-2-(p-tolyl)ethyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate

InChIKey: UFPINDDCTUCUSA-DFIYOIEZSA-N

SMILES: CC(C=C1)=CC=C1C[C@@H](NC2=CC=CC=C2)[C@]34C(C(OC)=O)=C(C(OC)=O)[C@@H](O4)C=C3

Biological Activity: COH000 is an allosteric, covalent and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) (E1), with an IC50 of 0.2 μM for SUMOylation in vitro[1].

Cat. No. Product Name Purity Description Pricing
HY-114304
COH000 98.0% COH000 is an allosteric, covalent and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) (E1), with an IC50 of 0.2 μM for SUMOylation in vitro.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References