1537150-15-4
1537150-15-4
Chemical Structure
SMN2 modulator-1
- CAS No.: 1537150-15-4
- Formula:C14H12ClFN2O2S
- Molecular Weight:326.77
IUPAC Name: 3-chloro-4-fluoro-N-(5-(1-hydroxycyclobutyl)thiazol-2-yl)benzamide
InChIKey: ILXVNGJDYBXBLK-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C(Cl)=C1)F)NC2=NC=C(C3(CCC3)O)S2
Biological Activity: SMN2 modulator-1 is a brain-penetrant survival motor neuron (SMN) modulator. SMN2 modulator-1 post-translationally stabilizes SMN protein and increases SMN protein levels independent of SMN2 transcription. SMN2 modulator-1 can be used for the research of spinal muscular atrophy[1].
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SMN2 modulator-1 | SMN2 modulator-1 is a brain-penetrant survival motor neuron (SMN) modulator. SMN2 modulator-1 post-translationally stabilizes SMN protein and increases SMN protein levels independent of SMN2 transcription. SMN2 modulator-1 can be used for the research of spinal muscular atrophy. | |||||||||||||||||||||
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