1539276-38-4
1539276-38-4
Chemical Structure
Plm IV inhibitor-2
- CAS No.: 1539276-38-4
- Formula:C39H54N4O4
- Molecular Weight:642.87
IUPAC Name: N1-((2S,3R)-3-hydroxy-4-((2-(3-methoxyphenyl)propan-2-yl)amino)-1-phenylbutan-2-yl)-5-(piperidin-1-yl)-N3,N3-dipropylisophthalamide
InChIKey: YKGWCOPGFKGNGN-MPQUPPDSSA-N
SMILES: CCCN(CCC)C(C1=CC(C(N[C@H]([C@H](O)CNC(C)(C2=CC(OC)=CC=C2)C)CC3=CC=CC=C3)=O)=CC(N4CCCCC4)=C1)=O
Biological Activity: Plm IV inhibitor-2 (compound 3) is a potent digestive vacuole plasmepsins IV (Plm IV) inhibitor with IC50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria caused by Plasmodium parasites[1].
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Plm IV inhibitor-2 | Plm IV inhibitor-2 (compound 3) is a potent digestive vacuole plasmepsins IV (Plm IV) inhibitor with IC50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria caused by Plasmodium parasites. | |||||||||||||||||||||
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