154164-30-4
154164-30-4
Chemical Structure
YM90K
- CAS No.: 154164-30-4
- Formula:C11H8ClN5O4
- Molecular Weight:309.67
IUPAC Name: 6-(1H-imidazol-1-yl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione hydrochloride
InChIKey: UMLFDVOHVJPDIZ-UHFFFAOYSA-N
SMILES: O=C1NC2=C(C=C(N3C=CN=C3)C([N+]([O-])=O)=C2)NC1=O.[H]Cl
Biological Activity: YM90K is a potent and selective AMPA receptor antagonist with a Ki of 84 nM. YM90K is less potent in inhibiting kainate (Ki of 2.2 μM) and NMDA (Ki of 37 μM) receptors. YM90K has neuroprotective actions[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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YM90K | 98.32% | YM90K is a potent and selective AMPA receptor antagonist with a Ki of 84 nM. YM90K is less potent in inhibiting kainate (Ki of 2.2 μM) and NMDA (Ki of 37 μM) receptors. YM90K has neuroprotective actions. | ||||||||||||||||||||
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Ro 48-8587 | Ro 48-8587 is a selective AMPA receptor antagonist with an IC50 of 8 nM. Ro 48-8587 functionally inhibits AMPA receptor activity, blocks AMPA-induced depolarization of rat cortical wedges. Ro 48-8587 can be used for the research of ischaemia and seizures. | |||||||||||||||||||||
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Licostinel | 98.12% | Licostinel (ACEA-1021) is a glycine receptor antagonist (IC50: 59 nM). Licostinel has neuroprotective activity. | ||||||||||||||||||||
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CNQX | 99.38% | CNQX (FG9065) is a potent and competitive AMPA/kainate receptor antagonist with IC50s of 0.3 μM and 1.5 μM, respectively. CNQX is a competitive non-NMDA receptor antagonist. CNQX blocks the expression of fear-potentiated startle in rats. | ||||||||||||||||||||
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DNQX (Standard) | ≥98% | DNQX (Standard) is the analytical standard of DNQX. This product is intended for research and analytical applications. DNQX (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively). | ||||||||||||||||||||
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NBQX | 99.82% | NBQX (FG9202) is a highly selective and competitive AMPA receptor antagonist. NBQX has neuroprotective and anticonvulsant activity. | ||||||||||||||||||||
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YM 900 | YM 900 is an AMPA receptor antagonist. | |||||||||||||||||||||
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Zonampanel | 99.02% | Zonampanel (YM 872) is a selective antagonist of the glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor. | ||||||||||||||||||||
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Becampanel | Becampanel (AMP397) is the first competitive AMPA antagonist and an antiepileptic agent. | |||||||||||||||||||||
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6,7-Diaminoquinoxaline-2,3-dione dihydrochloride | 6,7-Diaminoquinoxaline-2,3-dione dihydrochloride is a fluorescent dye that reacts with aldehydes. | |||||||||||||||||||||
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3,6-Dinitro-9H-carbazole | 3,6-Dinitro-9H-carbazole(3,6-Dinitrocarbazole) is a metal-organic framework (MOF). | |||||||||||||||||||||
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