1542213-00-2
1542213-00-2
Chemical Structure
NCT-502
- CAS No.: 1542213-00-2
- Formula:C18H20F3N5S
- Molecular Weight:395.45
IUPAC Name: N-(4,6-dimethylpyridin-2-yl)-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine-1-carbothioamide
InChIKey: HHKPPMSUPATMKP-UHFFFAOYSA-N
SMILES: S=C(NC1=NC(C)=CC(C)=C1)N2CCN(CC2)C3=NC=C(C=C3)C(F)(F)F
Biological Activity: NCT-502 is a human phosphoglycerate dehydrogenase (PHGDH) inhibitor, cytotoxic to PHGDH-dependent cancer cells, and reduces glucose-derived serine production, with an IC50 of 3.7 μM against PHGDH[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NCT-502 | 98.59% | NCT-502 is a human phosphoglycerate dehydrogenase (PHGDH) inhibitor, cytotoxic to PHGDH-dependent cancer cells, and reduces glucose-derived serine production, with an IC50 of 3.7 μM against PHGDH. | ||||||||||||||||||||
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