1551528-06-3
Chemical Structure
tri-GalNAc-C10-COOH
- CAS No.: 1551528-06-3
- Formula:C73H130N10O30
- Molecular Weight:1627.88
IUPAC Name: 1-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-16,16-bis((3-((3-(5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanamido)propyl)amino)-3-oxopropoxy)methyl)-5,11,18-trioxo-14-oxa-6,10,17-triazanonacosan-29-oic acid
InChIKey: PIVNBUXKJFLQQG-MTBPWAJSSA-N
SMILES: C(COCCC(NCCCNC(CCCCO[C@H]1[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O1)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]2[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]3[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)=O)=O)NC(CCCCCCCCCCC(O)=O)=O
Biological Activity: tri-GalNAc-C10-COOH (P290 232) is a targeted delivery intermediate composed of a trivalent N-acetylgalactosamine (GalNAc) cluster attached to a C10 linker ending with a carboxylic acid (-COOH) group. tri-GalNAc-C10-COOH is a standard building block used to synthesize LYTACs (lysosome-targeting chimeras) and cell-specific oligonucleotides like siRNA or ASO therapeutics[1].
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tri-GalNAc-C10-COOH | tri-GalNAc-C10-COOH (P290 232) is a targeted delivery intermediate composed of a trivalent N-acetylgalactosamine (GalNAc) cluster attached to a C10 linker ending with a carboxylic acid (-COOH) group. tri-GalNAc-C10-COOH is a standard building block used to synthesize LYTACs (lysosome-targeting chimeras) and cell-specific oligonucleotides like siRNA or ASO therapeutics. | |||||||||||||||||||||
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