155158-70-6
155158-70-6
Chemical Structure
(+)-(3S)-ψ-Ribalinine
- CAS No.: 155158-70-6
- Formula:C15H17NO3
- Molecular Weight:259.30
InChIKey: DWGJDUGVGKBCGA-LBPRGKRZSA-N
SMILES: O=C1C2=C(OC(C)([C@H](C2)O)C)C3=CC=CC=C3N1C
Biological Activity: (+)-(3S)-ψ-Ribalinine is an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with an IC50 of 62.46 μM against electric eel acetylcholinesterase and an IC50 of 150.04 μM against equine butyrylcholinesterase. (+)-(3S)-ψ-Ribalinine can be used for the research of neurological disorders[1][2].
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(+)-(3S)-ψ-Ribalinine | (+)-(3S)-ψ-Ribalinine is an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with an IC50 of 62.46 μM against electric eel acetylcholinesterase and an IC50 of 150.04 μM against equine butyrylcholinesterase. (+)-(3S)-ψ-Ribalinine can be used for the research of neurological disorders. | |||||||||||||||||||||
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References
- [1]. Sultana N, et al. A new fatty ester and a new triterpene from Skimmia laureola. Natural product research. 2008 Jan 10;22(1):37-47. [Content Brief]
- [2]. Derek R. Boyd, et al. Synthesis and absolute stereochemistry assignment of enantiopure dihydrofuro- and dihydropyrano-quinoline alkaloids. J. Chem. Soc., Perkin Trans. 1 2000; 29 (20): 3397-3405.
