155179-15-0
Chemical Structure
Zaragozic acid D2
- CAS No.: 155179-15-0
- Formula:C36H50O14
- Molecular Weight:706.77
IUPAC Name: (1S,3S,4S,5R,6R,7R)-1-((E)-4-acetoxy-5-methyl-8-phenyloct-7-en-1-yl)-6-(decanoyloxy)-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
InChIKey: WDLYATMIWWDJQY-FYSMYQDTSA-N
SMILES: CCCCCCCCCC(O[C@@H]1[C@@H](O)[C@@]2(CCCC(OC(C)=O)C(C)C/C=C/C3=CC=CC=C3)O[C@H](C(O)=O)[C@@]([C@@]1(O2)C(O)=O)(O)C(O)=O)=O
Biological Activity: Zaragozic acid D2 is the inhibitor for squalene synthase and Ras farnesyl-protein transferase (Ras FPTase), with IC50 of 2 nM and 100 nM, respectively. Zaragozic acid D2 is potentially ameliorating hypercholesterolemia and Ras-induced cancer[1].
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Zaragozic acid D2 | Zaragozic acid D2 is the inhibitor for squalene synthase and Ras farnesyl-protein transferase (Ras FPTase), with IC50 of 2 nM and 100 nM, respectively. Zaragozic acid D2 is potentially ameliorating hypercholesterolemia and Ras-induced cancer. | |||||||||||||||||||||
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